Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness
Pérez-Guisado JJakeman PM
Evidence is still building up
Summary
An RCT examining a single 8 g dose of citrulline malate during bench press to exhaustion in trained males. Versus placebo, repetitions increased by an average of 52.92%, post-exercise muscle soreness (DOMS) fell by 40%, and perceived fatigue was significantly lower. It demonstrates a single-dose pre-workout effect, but the design is short-term with a relatively small sample.
Key findings
- 1
Citrulline malate increased bench press repetitions by an average of 52.92%
- 2
Delayed onset muscle soreness (DOMS) decreased by 40%
- 3
Perceived fatigue was significantly lower than control group
Related supplements
PR
Improved muscular endurance (increased repetitions confirmed in research)
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Last checked: 2026-06-23